Epistane from IBE Technologies is a pro-anabolic anti-estrogen supplement which seeks to aid lean mass gains and claims the ability to protect from Gynocomastia.
IBE's Product Description:
Finally the PRO-Anabolic, anti-estrogen we have all been waiting for has arrived! Epistane™, exhibits a strong, long lasting anti-estrogen effect that is organ tissue specific. This means it works only where you want it to work. Broad range estrogen blockers and aromatase inhibitors can result in system shut down, aching joints, and decreased IGF-I expression. Epistane™ binds specifically to the 17ß-estradiol receptor protein in the target tissues. Because of its long lasting and strong effects on specific tissue, Epistane™ can significantly reduce and reverse the effects of gynocomastia because not only does Epistane™ specifically block estrogen in breast tissue but it induces an estrogen-depleted condition which leads to apoptosis or the death of the breast tissue cells. Studies show that small doses of the parent compound, Epitiostanol, at just 10-20mg/week showed a complete disappearance of the mass and pain in 25% of the male patients in the clinical trail, while the other 75% of the patients showed at least a 50% reduction in the mass and complete loss of pain in just 4-8 weeks. That’s results in 100% of the male users with no side effects. While compounds such as Clomid and Nolvadex also block the 17ß-estradiol receptor, they do not elicit the same increase in protein synthesis and strength gains that Epistane™ can offer.
Epistane™ is more than an anti-estrogen, though, as it also binds to androgen receptors in skeletal muscle. As a PRO-Anabolic compound Epistane™ promotes increases in strength and lean body mass with an anabolic/androgenic value (Q ratio) of 12. With most powerful androgens there is a high risk of the natural suppression of the gonads. Epistane™, unlike other PRO-Anabolic compounds that have recently been released, is relatively mild on the ...